- First woman Prime Minister of Tunisia - Najla Bouden Romdhane
- Newly elected Prime Minister of Japan – Fumio Kishida (100th Japanese Prime Minister)
- The volcano on La Palma Island in Atlantic Ocean that erupted in September 2021 after 50 years - Cumbre Vieja
- Service Company launched by central government in September 2021 to manage the asset and engage market professionals - India Debt Resolution Company Ltd. (IDRCL)
- Name the institution that launched 35 crop varieties to address the twin challenges of climate change and malnutrition - Indian Council of Agricultural Research (ICAR)
- Country that successfully tested nuclear capable hypersonic missile in September 2021 – North Korea
- First malayali to get Oman’s long term residence card for foreign investors – M A Yusuffali
- New society launched in Kerala to bring in different aspects of all organ donations and organ transplant surgeries under a single entity - Kerala State Organ and Tissue Transplant Organisation (KESOTTO)
- Famous film costume designer who died in September 2021 - Natarajan
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Sep