- The recipient of the Booker Prize 2021
- Damon Galgut(Novel – The Promise)
- Winner of the 33rd Jimmy George Foundation Award for Best Athlete in Kerala
- Aparna Balan (Badminton Player)
- Head of the 7 member IT Projects Advisory Committee (IT – PAC) of SEBI to provide guidelines on upgrading SEBI’s existing IT Systems
- Abhay Karandikar
- India’s first Indigenous Covid Vaccine to receive WHO approval for emergency use in November 2021
- Covaxin
- Word of the Year 2021 by the Oxford English Dictionary (OED)
- Vax
- The warship to be commissioned by Indian Navy in November 2021
- INS Visakhapatnam
- The state that topped in the best governed states according to the 6th Public Affairs Index (PAI) 2021 released by the Public Affairs Centre
- Kerala (Among large states)
(Among small states 1st – Sikkim, Among union territories 1st – Puducherry)
- The player who holds the record of most successful captain in T20 International Cricket in November 2021
- Eoin Morgan (England)
(He surpassed M.S Dhoni and Asghar Afghan (Former Afghanistan Captain)
- The Indian to win Bronze Medal in AIBA Men’s World Boxing Championship 2021
- Akash Kumar (54 kg category)
- Panchayat & Rural Development Minister of West Bengal who passed away in November 2021
- Subrata Mukherjee